|
Beckwith–Wiedemann syndrome (; abbreviated BWS) is an overgrowth disorder usually present at birth, characterized by an increased risk of childhood cancer and certain congenital features. Beckwith syndrome can also cause child behavior problems. Common features used to define BWS are: * macroglossia (large tongue), * macrosomia (above average birth weight and length), * midline abdominal wall defects (omphalocele/exomphalos, umbilical hernia, diastasis recti), * ear creases or ear pits, and * neonatal hypoglycemia (low blood sugar after birth). == History == Originally, Dr. Hans-Rudolf Wiedemann coined the term exomphalos-macroglossia-gigantism (EMG) syndrome to describe the combination of congenital abdominal wall defects as hernia (exomphalos), large tongues (macroglossia), and large bodies and/or long limbs (gigantism). Over time, this constellation was renamed Beckwith–Wiedemann syndrome following the autoptical observations of Prof. John Bruce Beckwith, who observed also severe increase in the size of the adrenal glands in some of these patients. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Beckwith–Wiedemann syndrome」の詳細全文を読む スポンサード リンク
|